Surface Bioactivation of metallic Biomaterials Thru Electrochemical Techniques

Tissue engineering and development of biomedical devices depend significantly on the functions and performance of biomaterials in the human body. Numerous metallic materials have been developed to meet new biomedical requirements and functionality as a result of the progress in material science and technology. Starting from simple load bearing, many specific functions of the biomedical metals such as bioactivity, anti-microbial function, drug loading, and even anti-tumour function have been developed. Surface characteristics influence how biomaterials and biological entities interact at the interface.
Surface engineering design is an important and predominant domain for developing materials with bio-function and biocompatibility intended to be used in medical applications. The biofunctionalization technique is a process that changes the surface composition, structure and morphology of a material, while maintaining the bulk mechanical properties intact.
Numerous methods of bioactivation techniques, both wet and dry, have been developed to enhance the hard tissue compatibility of metallic biomaterials. Many of these surface functionalization techniques have been used on Ti and its alloys, starting with simple mechanical techniques followed by electrochemical deposition of undoped and doped hydroxyapatite with Ag, Zn or Mg or anodic oxidation, with the aim of enhancing the osteointegration ability. The modified properties of new surfaces such as roughness, wettability, morphology, crystalline structure, corrosion resistance or bioactivity were investigated.
By using the proper biofunctionalization techniques as a tuning lever, the metallic biomaterials surfaces can be tailored to meet the biological requirements.

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Biography

Dr. Cosmin M. Cotrut is Associate Professor at the National University of Science and Technology Politehnica Bucharest, Faculty of Materials Science and Engineering. He published 7 books and book chapters (Springer Nature, Elsevier), over 100 peer reviewed scientific papers with Hirsch index 23, total number of citations 1500+. He was invited professor in other foreign universities (Ecole Polytechnique Universitaire de Lille, France and Tomsk Polytechnic University, Russia). The main research interest is related to degradation and corrosion of biomaterials with outstanding contributions related to the field of surface biofunctionalization methods for enhance of osseointegration and inducing antibacterial properties (biomimetic coatings of hydroxyapatite doped or co-doped with Mg, Sr, Ag, Zn by electrochemical methods), improving biocompatibility and tribological properties (thin layers based on nitrides, carbides, oxides or metallic glasses with the help of PVD techniques), the control of the degradation of biodegradable alloys (polymer based and PVD coatings) and the development of new Ti-based biocompatible alloys obtained both through clasic methods and additive manufacturing techniques, but also their biofunctionalization through nanostructuring and/or coating their surfaces. He serves as editor at different prestigious publishing houses (Editorial Board Member for Scientific Reports - Springer Nature, Heliyon- CellPress, Coatings - MDPI or Guest Editor for Thin Solid Films - Frontiers in Materials).